Moxidectin is a second-generation macrocyclic lactone of the milbemycin family. Praziquantel is a parasiticide widely used in many species for the specific control of tapeworm. For the single dose treatment of mixed cestode and nematode or arthropod infections in horses and ponies; caused by moxidectin and praziquantel sensitive strains of:
Large redworm (large strongyles):
- Strongylus vulgaris (adults)
- Strongylus edentatus (adults)
- Triodontophorus brevicauda (adults)
- Triodontophorus serratus (adults)
- Triodontophorus tenuicollis (adults)
Small redworm (small strongyles/cyathostomin) (adults and intraluminal larval stages):
- Cyathostomum spp.
- Cylicocyclus spp.
- Cylicostephanus spp.
- Cylicodontophorus spp.
- Gyalocephalus spp.
Ascarids:
- Parascaris equorum (adults)
Other roundworm species:
- Oxyuris equi (adults)
- Habronema muscae (adults)
- Strongyloides westeri (adults)
- Trichostrongylus axei (adults)
Bots:
- Gasterophilus intestinalis (L2, L3)
- Gasterophilus nasalis (L2, L3)
Tapeworm:
- Anoplocephala perfoliata
- Anoplocephala magna
- Anoplocephaloides mamillana
The egg reappearance period of small redworm is 90 days.
The product is effective against (developing) intramucosal L4 stages of small redworm. At 8 weeks after treatment, early (hypobiotic/inhibited) EL3 stages of small redworm are eliminated.
The product is effective against benzimidazole resistant strains of cyathostomes
For oral administration. One 11.8g syringe contains sufficient gel to treat a 575kg horse at the recommended dose rate (0.4mg moxidectin per kg bodyweight and 2.5mg praziquantel per kg bodyweight). Each graduation on the calibrated syringe delivers sufficient gel to treat 25kg bodyweight. Use of a scale or weight tape is recommended to ensure accurate dosing. To avoid overdosing, care should be taken to accurately dose foals, especially low bodyweight foals or pony foals.
Dosing guideline
The recommended dosing interval for the control of small redworm is 13 weeks. For optimum control of bots, the product should be administered in the autumn, after the end of the fly season and before spring as the larvae may start to pupate and therefore are less sensitive to treatment.
Veterinary advice should be given on appropriate dosing programmes and stock management to achieve optimum parasite control.
